Jyotsna S Shah, PhD 2019

Palo Alto, CA
Laboratory Director
IGeneX Laboratory


Dr. Jyotsna Shah is the Vice-President and Laboratory Director of IGeneX Laboratory, Palo Alto, CA. Dr. Shah has over 35 years of research experience in immunology, molecular biology and microbiology. She received her BSc and MSc in Biological Sciences from UK and her PhD in diagnostic immunology from Nairobi University. She then joined the International Laboratory for Research on Animal Diseases (ILRAD) as a post-doctoral scientist where she started the first DNA sequencing laboratory in E. Africa. On completion of her fellowship, she joined Harvard University, Department of Tropical Medicine as a research fellow and continued work on development of molecular tools for diagnosis of parasitic diseases.

Since then she has worked at several Biotechnology companies, mostly involved in development of novel molecular technologies for diagnosis of infectious diseases. Dr. Shah is a world expert on use of Fluorescent in Situ Hybridization (FISH) technique for direct detection of pathogens in clinical samples. For the last 18 years, she has been at IGeneX, where she introduced the first FISH test for Babesia and set up the PCR division for tick-borne diseases. Under her scientific guidance IGeneX has become one of the leading reference laboratory for diagnosis of tick-borne diseases in the world.


Topic: Morgellons Disease – Is it a Chronic form of Borrelia and/or Bartonella Infection?

Morgellons disease has been associated with Borrelia infections. We performed a study on 29 well characterized patients with Morgellons disease. All the patient blood samples were tested for Borrelia burgdorferi group, Relapsing Fever Borrelia group, Babesia, Ehrlichia and Bartonella by immunological and molecular methods. We were able to detect antibodies or DNA of Borrelia burgdorferi group, Relapsing Fever Borrelia group and Bartonella in these patients. Surprisingly none of the patients were positive for Ehrlichia or Babesia in this group.