You’re trying to work, but the work isn’t happening. Concentration flits in and out, allowing you to only make mild headway on what you’re supposed to be doing. The dishes and the laundry are stacking up. You haven’t the energy to shower. You’re so tired. All the time. And you’ve been tired for weeks, maybe even months. 

When will this chronic fatigue go away? 

If you have Morgellons disease, the above description may sound too familiar. Many Morgellons patients haven’t even thought that fatigue and an inability to concentrate could be tied to a physical ailment that’s all too often categorized as a mental disease. 

After all, it’s always easy to find another culprit for your tiredness. Maybe you blame how you’re feeling on not getting enough sleep. Maybe you just think you’re in the wrong state of mind. Maybe you think you’re overly busy. Could be that you tie it to just getting older. 

But you may be selling yourself short. 

Morgellons disease is typically characterized by slow-healing open sores and colored filaments embedded in and protruding from the patient’s skin. However, patients also experience all-consuming fatigue and many symptoms of chronic inflammation. 

Because many of these symptoms are non-descript, Morgellons patients are frequently misdiagnosed for other ailments and don’t receive the treatments they desperately need. 

Morgellons is pathological—not psychiatric. Patients must be treated with antibiotics, not antipsychotics, to manage their symptoms. Until patients can resolve the underlying infection, they will be trapped in a never-ending inflammation/fatigue cycle. 

In this article, The Charles E. Hollman Morgellons Disease Foundation will explore how the underlying bacterial infection triggers symptoms of inflammation and the resulting fatigue and what this means for patients with the disease. 

Inflammation 

Generally, inflammation is the body’s process of responding to an irritant. The irritant could be an invader like a bacteria or virus or a foreign object like a splinter. The inflammation process starts when our bodies are trying to fight off the irritant. 

The inflammatory immune response involves a highly coordinated series of molecular communications between different immune cells and blood vessels. These communications cause: 

• Fever
• Redness
• Swelling
• Pain 
• Loss of function 

What happens when you have inflammation 

There are many different immune cells involved in causing inflammation. These cells release “inflammatory mediator” hormones that send signals to small blood vessels in the tissues to open up. As the blood vessels dilate or become more expansive, more blood can reach the injured area. This is why inflamed areas become red and feel hot to the touch. 

Increased blood flow also allows more immune or white blood cells to flood the area where they can fight invaders and start the healing process. 

Inflammation mediators or chemical signals make it easier for white blood cells to squeeze through the walls of blood vessels so that they can enter the infected tissues. When the white blood cells enter the tissues to attack and remove infectious invaders like bacteria or viruses, more fluid also enters the tissues causing swelling.  

Inflamed areas of the body often become painful to the touch because the inflammatory signaling hormones also trigger pain receptor nerves, sending pain signals to the brain. The more the inflammation hurts, the more likely the patient will be to protect the injured area. 

Swelling and pain aren’t the only symptoms patients experience during inflammation. Patients who are fighting an ongoing infection may also experience extreme fatigue. 

Fatigue

Fighting off an ongoing infection takes a lot of energy; as a result, the body changes how it accesses nutrients to get necessary energy faster. Unfortunately, the short-cut pathways our bodies use to access energy under stress are much less efficient than those used when the body is not sick. As a result, patients fighting ongoing infections may become extremely tired. 

Patients suffering from chronic fatigue may feel so depleted that they can’t manage their everyday lives—and this intense exhaustion can last for months or even years. Chronic or persistent fatigue is different from acute fatigue. 

Acute fatigue is a healthy, adaptive response to physical or mental exertion. Persistent fatigue doesn’t go away after sleeping in on the weekend or taking an extra nap in the afternoon. 

Patients with persistent fatigue may find it hard to get up in the morning to go to work or do their regular daily activities. Instead, they muddle through, fighting an intense urge to sleep. When patients try to sleep, they may never feel fully rested or refreshed despite being asleep for hours.  

Those suffering from persistent fatigue may develop depression, lack motivation, and become anxious as their symptoms persist.

Relationship between fatigue and inflammation

Inflammation triggers a change in metabolism—how the body makes and uses energy—which causes fatigue. 

Patients suffering from persistent infections experience prolonged inflammation, causing an increase in insulin resistance, reduced glucose uptake by white blood cells, and less overall energy production. 

The body uses nutrients from the foods we eat to create the energy necessary to run our physiological processes and help us live our daily lives. When experiencing prolonged infections and the resulting inflammation, the body diverts energy from other systems to support the immune system. 

Essentially, fighting an ongoing infection triggers inflammation, and the accompanying fatigue forces the patient to rest to conserve energy for the massive immune response. 

What does this mean for Morgellons patients? 

Among the long list of symptoms that Morgellons patients experience, debilitating fatigue resulting from an intense inflammatory response is near the top of the list. 

Morgellons patients can be profoundly tired, so much so that they cannot work or even care for themselves. Patients may also experience painfully swollen joints and intense muscle pain triggered by a prolonged inflammatory response. These symptoms may last for months or even years without letting up. 

Despite what the CDC and the mainstream media report, many studies have found that Morgellons patients suffer from an ongoing bacterial infection. Nearly all Morgellons patients have tested positive for Borrelia burgdorferi, a spirochetal bacteria spread through bites from the Black-legged tick—the same tick that causes Lyme disease. 

Left untreated, the infectious spirochete spreads throughout the patient’s body, triggering inflammation and causing damage. These specially adapted bacteria can swim through dense tissues and outrun immune cells as they disseminate. In patients with ongoing infections, spirochetes have been found in the heart, joint, muscle, and brain tissues. 

As the patient’s immune system battles the invading spirochete, energy packets are diverted from functional systems to the front lines of the immune response, leaving the patient literally drained and unable to exert any extra energy toward living their daily lives. 

Until the patient can get the underlying infection under control, they will never be able to break the inflammation/fatigue cycle and will continue to suffer. The Charles E. Holman Morgellons Disease Foundation and thousands of people with Morgellons disease need your help. 

Your donations fund critical research and provide educational opportunities and resources for those with this debilitating disease.  Please consider donating today to help us release more Morgellons patients from the grip of inflammation and fatigue cycles.

 

Morgellons disease has enough in common with Lyme disease that finding a knowledgeable doctor can be difficult. But the cost of not finding one is even greater. 

If you feel you have Morgellons and need to find a doctor who understands, keep reading to learn what’s at stake and how you can best get help and understand this often mischaracterized disease.

Patients with Morgellons disease suffer from slow-healing open sores, extreme fatigue, and a host of other symptoms, including joint pain, heart problems, crawling skin sensations, and mental decline. 

Unfortunately, because Morgellons isn’t widely recognized, many patients suffer without knowing the root cause of their symptoms. Morgellons patient symptoms are often dismissed as a delusional disorder because patients feel like something is crawling through their skin and insist that something is wrong with them. 

Unable to explain these symptoms, doctors conclude that patients are experiencing a psychotic event and scratching themselves, causing open sores. It’s no big surprise since the Center for Disease Control’s landmark research missed the mark by characterizing the disease as a mental and physical deterioration loop that preys on itself. 

Physical symptoms of Morgellons, they said, compound on pre-existing insecurities, anxiety, and mood disorders. The mental anguish, in turn, feeds the physical manifestations, deepening the hold of the mental problems just to repeat the loop again.

Dismissive medical professionals aside, real, erratically growing fibers embedded deep within the skin cause Morgellons patients’ skin discomfort. These fibers are a  hallmark identifier of Morgellons disease but can only be seen by handheld light microscopes under 50x magnification. 

Compared to collagen and keratin fibers, the normal structural fibers found in skin, Morgellons fibers are so large that patients can sometimes feel them growing between their tissues. That constant creepy-crawling sensation is nerve-wracking enough to come across as a mental disorder. Add to that disfiguring skin sores, extreme fatigue, and debilitating joint pain, and it’s no wonder many Morgellons patients experience a poor quality of life. 

Sadly, too many Morgellons patients suffer silently and without hope as doctors dismiss symptoms as psychological issues and they never receive needed treatments. As a result, patients continue to suffer because their symptoms are masked instead of resolved. 

Through ground-breaking research funded by the Charles E. Holman Morgellons Disease Foundation, we now have evidence that Morgellons is more than a delusional disorder: 

Morgellons is a genuine somatic illness caused by an underlying bacterial infection and can be treated, or at least managed, with an antibiotic regimen. 

Pathogenic infection

Nearly all Morgellons patients studied tested positive for a Borrelia burgdorferi infection, or Borreliosis. Borrelia burgdorferi is the same bacteria that causes Lyme disease and is in the same classification as the bacteria that causes Syphilis—both are spirochetes. 

Morgellons patients “catch” the disease after being bit by the black-legged tick. The tick carries the infection in its gut, sharing it anytime it feeds on a new host—including humans. 

Unfortunately, many tick bites go unnoticed. Patients may not even realize a tick bit them after visiting tick-infested areas and are left puzzling through emergent symptoms months or even years later. 

Borrelia burgdorferi is a flagellated spirochete; this means that the long, narrow body of the bacteria has many whip-like tails that it can use to “swim” through fluids and tissues. The spirochete is much smaller than human tissue cells and can quickly move through dense tissues or even pass through cell walls—well out of reach of a patient’s white blood cells.  

This spirochete is so good at moving around it can outrun a patient’s immune cells and doesn’t need to travel through the bloodstream to spread throughout the body. Left untreated, the pathogen can disseminate or travel to other body areas and invade cells far from the infection site. 

Morgellons patients suffer from many different symptoms because the infecting spirochete spreads prolifically. In many studies, live Borrelia burgdorferi colonies were found in the heart, connective tissue, brain, and nerve cells. 

Diagnosis

The key to successful borreliosis infection treatment depends on early identification and antibiotic therapy. However, for several reasons, only some patients can get the help they need. 

One of the most significant setbacks for patients is that since the underlying spirochetal infection can lie dormant for months or even years before symptoms manifest, many patients don’t know they need medical help. When symptoms do manifest, the bacteria have built a stronghold within the body, spreading so prolifically that it’s nearly impossible to eradicate. 

The other major hurdle patients face is that many medical professionals are either unaware of Morgellons disease or deny that an infectious agent causes it. That is to say that many doctors aware of Morgellons chalk it up as a delusion and send patients off for psychiatric care instead of antibiotic therapy. That of course, reinforces or even creates anxieties and may actually feed the negative mental/physical feedback loop the CDC described.

The fact that testing for Borreliosis presents many challenges doesn’t help matters either:

• Blood testing inaccuracies result in many false negatives
• Cultural growth and staining are time-consuming and expensive 
• DNA testing for the bacteria is both expensive and may be inaccurate as the DNA in laboratory strains of the bacteria differ from strains in the wild

Looking for characteristic Morgellons skin fibers using hand-held light microscopy is the easiest and most effective way to diagnose Morgellons disease clinically, but not enough medical professionals know to use this technique. 

It’s true that bull-eye rashes, or erythema migrans rashes, are a tell-tale sign of a tick bite and an underlying Borrelia burgdorferi infection. Still, only a handful of people develop the rash, so it’s no reliable metric for infection diagnosis. 

If these symptoms resonate with you, there is still hope. 

Finding hope

By funding research and grass-roots efforts, the Charles E. Holman Morgellons Disease Foundation is helping spread more awareness for this debilitating disease. Through donation collections, we can fund essential research and educate the public and the medical community about Morgellons so that more doctors become sympathetic toward patients’ suffering and willing to treat the underlying infection. 

For patients who feel they have exhausted every avenue, we ask that you click here to find a doctor who may be willing to help you. Additionally, please enter your demographic data into the registry we have created that assists scientists in tracking and researching this disease.  

Please donate to our foundation today to help stop misdiagnosis, improve our education and doctor network, and fund the research that will counter the harmful CDC findings that more than a decade of research has dispelled. 

Medical professionals often misdiagnose Morgellons disease symptoms. They may miscategorize them as other illnesses ranging from skin conditions to psychological disorders.

This leaves many patients without the care and treatments they need for relief.

All too frequently, doctors say nothing is physically wrong with their Morgellons patients. Instead, they attribute real symptoms to delusions of infestation—meaning the patient just thinks something has infected them. 

However, evidence supporting an infectious cause is stacking up. 

The majority of the medical community refuses to acknowledge Morgellons as an actual infectious disease, despite evidence on the contrary. 

To develop a clinical diagnosis, a research team led by Marianne J. Middelveen has proposed criteria for identifying and classifying Morgellons disease.

Morgellons overview

Morgellons is a complex skin disease characterized by ulcerating lesions (open sores) with protruding or embedded filaments. 

These filaments or fibers are made from the patient’s skin cells that have gone hay-wire. They’re made of the same protein, keratin, and collagen that make our hair, skin, and nails.  

Using hand-held light microscopes at 50x magnification, researchers can see filaments or fibers in the skin of Morgellons patients. The fibers may be blue, red, green, black, or white and are found growing under unbroken skin, protruding from calluses, and sprouting around skin lesions or open sores. 

Aside from the strange fibers and obviously painful open sores, patients suffering from Morgellons disease also experience symptoms consistent with unresolved Lyme disease. These symptoms involve many different body systems and severely impact a patient’s quality of life. A patient with Morgellons may experience all of these symptoms:  

• Extreme fatigue
• Muscle pain 
• Arthritis 
• Cardiac disease
• Memory loss
• Brain fog
• Depression and anxiety
• Disfiguring open sores

Through dozens of studies, researchers have discovered that 98% of Morgellons patients have an underlying Borrelia burgdorferi infection. Borrelia burgdorferi is a spirochetal bacteria spread through black-legged tick bites. They’re also the leading infectious agent in Lyme disease. 

These spirochetes have been positively identified in patient tissue and body fluid samples using cell culture growths, PCR testing, SEM, TEM, light microscopy, and various staining techniques. 

Morgellons patients account for up to 6% of Lyme disease diagnoses in Australia. This fact hints to researchers that persistent Lyme disease may manifest as Morgellons disease instead of a standalone illness. 

The spirochetes in Lyme disease and Morgellons persists after antibiotic therapy through various adaptations that allow it to outrun the patient’s immune system. The little parasites hide inside specific cells and slow growth until the treatment stops. 

Because of spirochete evasiveness, Morgellons disease is challenging to treat. Researchers and doctors haven’t yet discovered a practical course of antibiotic treatment that can permanently resolve the infection. 

Clinical Diagnosis for Morgellons

Partly because of the treatment and diagnosis issues associated with Morgellons, Middelveen’s research team created a clinical diagnosis scheme for Morgellons. The idea behind the research is to help medical professionals accurately diagnose and evaluate the severity of their patients’ illnesses. 

Medical classification schemes for disease staging help doctors objectively identify and assess disease severity and progression to prescribe the correct therapies and treatment

routes. Syphilis, another spirochetal infection characterized by skin lesions, is categorized by three stages that reflect an array of skin sores and lesions associated with the disease. 

Borrelia burgdorferi bacteria are the primary infectious agent that causes Morgellons disease. These flagellated spirochetes can “swim” through dense tissues and complex cellular structures, allowing them to travel or disseminate throughout the body of their hosts and infect a wide range of body tissues in various locations. In patients with a localized classification, the bacteria often haven’t yet spread beyond the body part that was initially bitten by the infectious tick. 

The “class” designations in the staging for Morgellons disease denote how long the patient has been experiencing symptoms and whether the symptoms are local to one area of the body or disseminated to include others.  

The “class” designations for the disease spread are paired with one of three varying stages of lesion progression. These stages help medical professionals assess the severity of the Borrelia infection. Stage A lesions are milder than Stage C lesions; Stage B lesions are somewhere between. 

Below we share the specific classes and stages of Morgellons disease.

Class I

Early localized: lesions and fibers have been present for less than three months and are found on one central body area such as the head, trunk, or extremities. 

Class II

Early disseminated: lesions and fibers have been present for less than three months and involve more than one area of the body. 

Class III

Late, localized: fibers/lesions have been present for more than six months and are found on one area of the body, such as the head, trunk, or extremities. 

Class IV

Late, disseminated: lesions and fibers have been present for more than six months and have spread to more than one body part. Patients may have lesions and fibers on their head, trunk, and extremities. 

Stage A 

During the first or early stage of Morgellons disease, the lesions have little immune cell reaction to the spirochetal infection. There are no macrophages (white blood cells) or hemorrhaging (bruising) in or around the lesions. 

The skin cell layers are still organized, and the keratinocytes—cells that make keratin—have not been pushed into overdrive by the invading spirochetes. 

Stage B

Patients with Stage B lesions have an intermediary pattern that has progressed beyond Stage A but hasn’t yet reached the advanced degree seen in Stage C. 

Stage C

White blood cells, macrophages, and Borrelia species colonies are easily found in late Stage C lesions samples. There’s remarkable bruising or hemorrhaging around the lesions, and the invading spirochetes have activated both Keratinocytes (keratin-producing cells) and fibroblasts (collagen-producing cells). The cells work in overdrive to produce unusual fibers and filaments. The skin cell layers in Stage C lesions have also been disrupted and are unorganized.

While identifying a clinical diagnosis can go a long way toward helping patients suffering from this disfiguring illness, there’s still much we don’t yet understand. 

Donate today

Our researchers have made huge strides over the last decade to understand this debilitating illness better. But we are still far from reaching a cure or gaining traction in the mainstream medical community. 

Only through grass-roots efforts can we spread awareness about the genuine impacts this disease has on Morgellons patients and their families. 

Please do

nate today to the Charles E. Holman Morgellons Disease Foundation so we can continue to fund more research like this and spread awareness. 

The mainstream media and the medical community at large view Morgellons as a delusional disorder. But research over the last decade has found that Morgellons disease symptoms are a manifestation of an underlying bacterial infection. The culprit, spirochetal bacteria in the Borellia genus, are known to cause disease in other mammals and are spread by blacklegged ticks. 

 

If you have Morgellons symptoms, you may have suffered for years before finding a name for your illness. The Charles E. Holman Morgellons Disease Foundation is here to help answer your questions surrounding Morgellons disease and raise awareness for healing. 

 

Through the remainder of this article, we’ll introduce how Morgellons symptoms spread through tick bites and how animals that contract the symptoms are cured. Then we’ll examine why people aren’t treated with known cures for the same symptoms, often being mislabeled with mental disorders instead.

How do you get a spirochetal infection? 

Understanding Morgellons disease requires knowing how ticks spread bacteria. Spirochetal bacteria, named for their spiral-shaped appearance, are responsible for many diseases. Borrelia, a group of spirochetes, causes infectious diseases like Morgellons, relapsing fever, and Lyme disease and is primarily spread through blacklegged tick bites.  

Ticks and disease

Ticks use unique sensory systems to detect the breath, body odor, body heat, and movement vibrations of animals. These adaptations allow the blacklegged tick to identify frequently used paths. 

 

Along these paths, ticks climb to the tips of shrubs and grasses and wait for their next hosts with arms outstretched—a behavior called questing. When an animal brushes by, the tick climbs aboard. 

 

Once on the host, ticks spend ten minutes to two hours looking for the right place to begin eating. Usually, ticks prefer moist, protected areas on the body that won’t be easily noticed, like the groin or ears. 

 

Once a tick has found the perfect spot to eat, it grasps the host’s skin and cuts through the surface layers. Next, the tick inserts a feeding tube and secretes a cement-like substance to hold it in place while it dines. 

 

While feeding, ticks excrete anesthetic laced saliva so that the host won’t be bothered by the feeding parasite. If the tick finds a well-sheltered spot, it can go unnoticed for its entire stay. 

 

Ticks usually suck blood for several days. Once they’ve had their fill, they’ll fall off. The host may be none the wiser. 

 

Problem is, ticks spread disease while they feed. If a host animal has a blood-borne illness, the tick ingests those germs during its meal. When the tick finds a new host, it then spreads those germs and illnesses through its saliva.

 

Blacklegged ticks seek a new host with every life stage. And since these ticks can live for three years, a single tick can spread disease through any number of animals—humans included.  

Symptoms of tick-borne illness

In many cases, people who contract tick-borne illnesses may never know that a tick bit them, and symptoms of a tick bite may take days or weeks to appear. 

 

If you like to go for adventures in tick-infested areas, take precautions to protect yourself from tick bites.

 

If you suspect you’ve experienced a tick bite, here are symptoms to watch for: 

 

• Fever and chills 
• Muscle aches and joint pain
• Extreme fatigue 
• Erythema migrans rash—“bullseye” rash

 

Generally speaking, an erythema migrans rash is a tell-tale sign of a Lyme infection. About 30% to 80% of infected people develop a rash that starts at the site of a tick bite. The rash can take anywhere from a few days to an entire month to show up after the bite, so you wouldn’t know that a tick bit you until after the tick is long gone. 

 

“Bullseye rashes,” or Erythema rashes, get their nickname because they gradually grow in a bullseye shape over several days and may be as large as 12 inches across. As the rash develops, it also clears, leaving a red mark in the center surrounded by a red rim along the outermost edge with clear skin in the middle. The rash is warm to the touch but isn’t itchy or painful. 

 

Evidence suggests that Morgellons patients suffer from a form of chronic, systemic Lyme disease. When a person goes untreated for a tick bite leading to Lyme disease, the spirochetal infection can spread, causing symptoms in several different body systems and even leaving microscopic fibrous growths embedded in the skin and causing itchiness. Research also suggests that humans aren’t the only mammals to react to a Borrelia infection with lesions and fiber growth. 

Borellia infections in other animals

As seen in Morgellons disease, extraordinary keratin fibers and ulcerating lesions aren’t unique to humans. These are well-known symptoms of spirochetal infections in domestic dogs and livestock. 

Lyme disease in dogs

Our canine companions are susceptible to tick-borne illnesses too. Dogs with tick-borne diseases like canine Lyme experience many of the same symptoms as humans, including: 

 

• General malaise
• Fever
• Swollen lymph nodes
• Joint pain
• Swollen connective tissues

 

However, furry friends can’t speak up and tell us that they aren’t feeling well, so initial symptoms may go unnoticed by owners for weeks or even months. Once noticeable symptoms like lameness become apparent, the underlying spirochetal infection has spread throughout the dog’s body. 

 

In 2016, researchers collected skin samples from nine dogs experiencing ulcerating lesions with unusual filament growth—strikingly similar to Morgellons disease. The dogs in question also had a history of tick exposure. 

 

Skin samples were examined under a microscope and used for culture growth. Researchers visually confirmed spirochetes under magnification, and the cultures grew a species of Borrelia bacteria. Researchers did not find the presence of Borrelia species in the asymptomatic dogs that were used as controls. That hints that the bacteria isn’t found in healthy canines and may be responsible for illness in the afflicted dogs. 

 

Through serological (blood plasma and antibody) testing, researchers found that most of the dogs had antibodies against Borrelia bacteria—which indicated that the animals’ immune systems in the study were fighting an ongoing infection. Again the control animals did not test positive for Borrelia antibodies and did not have an immunological history of the disease. 

 

In this study, owners of the infected dogs tried several different treatments to heal their pets’ sores and alleviate symptoms. In almost every case, topical treatments failed. Antibiotic therapies that included doxycycline were successful. 

Bovine digital dermatitis 

Since 1994, bovine digital dermatitis (BDD) has been a widespread and well-documented illness affecting dairy cattle in the midwestern United States. Characterized by open sores and long filaments, this disease can cause lameness, weight loss, a decrease in milk production, and even death in dairy cattle. The condition is highly contagious and can quickly spread through an entire herd, with devastating financial impacts for farmers. 

 

Because of BDD’s financial strain on the entire dairy industry, researchers quickly identified spirochetal infections as a primary cause. Over the last 20 years, antibiotic sprays and foot washes have been widely accepted treatments for infected animals. 

 

And yet antibiotic treatment for people with Morgellons still isn’t widely accepted. If you suffer from Morgellons disease symptoms and have been unable to find help, locate a doctor who understands now.

Your donation saves lives

Canine companions receive antibiotic treatment when a spirochetal infection causes open sores, general malaise, and unusual filament growths. 

 

Dairy cattle receive antibiotic treatment when a spirochetal infection causes open sores, filament growth, and decreased milk production. 

Yet when a person experiences a spirochetal infection with open sores, filament growth, and debilitating systemic symptoms, many experts call them “delusional.” 

Help us make Morgellons a disease acknowledged by practitioners as the debilitating disease it is. The harm and emotional turmoil that comes from misdiagnosis is too massive to adequately explain.

 

Help spread awareness and change the dogma surrounding Morgellons disease through grassroots efforts. Your donations help fund the research for practical solutions that can provide relief to those suffering from Morgellons disease.

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